How Does Nerivio Work?
Nerivio® is the first and only FDA-cleared device to utilize Remote Electrical Neuromodulation (REN) to prevent and treat migraine. Clinical trials demonstrate that Nerivio provides consistent relief of pain and associated migraine symptoms. It is safe and well-tolerated with no systemic side effects or concern for medication overuse.
You can access the Patient Support Program by calling 900 101 856, where you can get information about the use and functionalities of Nerivio®, as well as resolve any doubts and receive advice from a professional team of nurses.
Check bibliography
Lloyd J, Biloshytska M, Andreou AP, Lambru G. Noninvasive Neuromodulation in Headache: An Update. Neurol India. 2021 Mar-Apr; 69 (12 Suppl 1)
Acute treatment
Use Nerivio as often as needed for 45 minutes to treat every migraine
Preventive treatment
Use Nerivio as every other day for 45 minutes to prevent migraine
Look for detailed information in the Nerivio User manual
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A discreet, wearable device
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Drug-free, Non-invasive, Non-addictive
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Not disrupting to daily routine
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Can be used instead of or with medications
Novel Mechanism of Action
Nerivio stimulates Aδ and C fibers in the upper arm. Stimulation of these pain fibers sends messages to the pain regulation centers in the brainstem. This activates the body’s Conditioned Pain Modulation (CPM) system, activating the descending pain inhibitory pathways. Descending inhibitory signals travel to the trigeminal cervical complex where serotonin and norepinephrine are released. Nerivio’s activation of the body’s endogenous analgesic system has a global impact on pain.
